Anti-inflammatory-drug-induced pharmacodermia

Authors

DOI:

https://doi.org/10.46551/ruc.v27n2a4

Keywords:

Drug eruptions, Dermatitis medicamentosa, Adverse Drug Event

Abstract

Objective: to report a case of pharmacodermy treated at Clemente de Faria Hospital, and to discuss the diagnostic and therapeutic methods employed. Method: a descriptive observational case-report study, carried out through analysis of health records.  Discussion: the distribution of bullous lesions on the back of the neck, upper trunk and hands, in addition to intense eosinophilia, accompanied by increased C-reactive protein and liver enzymes, made the patient's condition similar to Drug-induced hypersensitivity syndrome / Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome (DIHS/DRESS). Final considerations: pharmacodermy are rare and potentially fatal. Case reports allow the construction of clinical reasoning that, associated with laboratory parameters, improve the quality of care and allow early identification of reactions.

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Author Biographies

Thércia Guedes Viana Bittencourt, Universidade Estadual de Montes Claros (UNIMONTES)

Doutora em Farmacologia. Professora do Departamento de Fisiopatologia, Universidade Estadual de Montes Claros (UNIMONTES). Montes Claros, MG, Brasil. https://orcid.org/0000-0001-9550-4292; e-mail: thercia.bittencourt@unimontes.br.

Mayra de Souza Veloso, Centro Universitário do Norte de Minas (FUNORTE)

Granduanda em medicina. Centro Universitário do Norte de Minas (FUNORTE) . Montes Claros, MG, Brasil. https://orcid.org/0000-0002-5482-4596; e-mail:mayraveloso16@yahoo.com.br

Marianna Lessa, Irmandade Nossa Senhora das Mercês- Santa Casa de Montes Claros

Médica. Irmandade Nossa Senhora das Mercês- Santa Casa de Montes Claros. Montes Claros, MG, Brasil.  https://orcid.org/0009-0005-0318-4356; e-mail: marianna.lessa@yahoo.com.br

Bárbara Nobre Lafetá, Universidade Estadual de Montes Claros (UNIMONTES)

Doutora em Ciência Animal. Professora do Departamento de Fisiopatologia, Universidade Estadual de Montes Claros (UNIMONTES). Montes Claros, MG, Brasil. https://orcid.org/0000-0002-5460-2416; e-mail: barbara.lafeta@unimontes.br

References

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Published

2025-08-08

How to Cite

GUEDES VIANA BITTENCOURT, Thércia; DE SOUZA VELOSO, Mayra; LESSA, Marianna; NOBRE LAFETÁ, Bárbara. Anti-inflammatory-drug-induced pharmacodermia. Revista Unimontes Científica, [S. l.], v. 27, n. 2, 2025. DOI: 10.46551/ruc.v27n2a4. Disponível em: https://www.periodicos.unimontes.br/index.php/unicientifica/article/view/8457. Acesso em: 15 jan. 2026.

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Section

Relatos de Casos